CBD can benefit those with schizophrenia because of its neuroprotective traits.

That’s because CBD may reduce symptoms of schizophrenia by stabilizing disrupted NMDA receptors in the brain.

NMDA receptors are neurotransmitter receptors that are located in the post-synaptic membrane of a neuron. They are proteins embedded in the membrane of nerve cells that receive signals across the synapse from a previous nerve cell.

NMDA receptors are involved in signal transduction and control the opening and closing of ion channels. They are believed to play an important role in learning and memory formation.

A double-blind controlled clinical trial was performed by Dr. F.M. Leweke comparing CBD with a prescription antipsychotic called amisulpride.

The trial tested the different treatments on 42 participants with acute paranoid schizophrenia. Both treatments led to a significant decrease in psychotic symptoms.

However, CBD had no negative side effects, whereas the amisulpride had several.

Schizophrenia Studies